Background：This gene encodes a member of the ADAM （a disintegrin and metalloprotease domain） family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.
仕様
Synonyms：A disintegrin and metalloproteinase domain 19 （meltrin beta）,A disintegrin and metalloproteinase domain 19,ADAM 19,ADAM metallopeptidase domain 19,Disintegrin and metalloproteinase domain containing protein 19,FKSG 34,FKSG34,MADDAM,Meltrin beta,Metalloprotease and disintegrin dentritic antigen marker,Metalloprotease disintegrin meltrin beta,MLTN B,MLTNB
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ADAM19
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：1000 - 1：2000
Gene_ID（human）：8728
Swissprot：Q9H013
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
