Background：This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed.
仕様
Synonyms：Adenosine 5' monophosphoramidase,Adenosine 5''-monophosphoramidase,HINT 1,HINT1,HINT1,Histidine triad nucleotide binding protein 1,Histidine triad nucleotide-binding protein 1,PKCI 1,PKCI-1,PKCI1,PRKCNH1,Protein kinase C inhibitor 1,Protein kinase C interacting protein 1,Protein kinase C-interacting protein 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human HINT1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：1000 - 1：2000
Gene_ID（human）：3094
Swissprot：P49773
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
