Background：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones （H2A, H2B, H3, and H4） form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17.
仕様
Synonyms：H3 histone family 3A,H3 histone family 3B,H3 histone,family 3B （H3.3B）,H3.3,H3.3A,H3.3B,H33,H3F3,H3F3A,H3f3b,Histone H3.3,Histone H3.3Q,Histone H3.A,Histone H3.B,MGC87782,MGC87783
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human H3F3B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3020
Swissprot：P84243
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
