Background：Succinyl-CoA synthetase （SCS） is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
仕様
Synonyms：A BETA,A SCS,ATP specific succinyl CoA synthetase subunit beta,ATP specific succinyl CoA synthetase, beta subunit,ATP-specific succinyl-CoA synthetase subunit beta,Mitochondrial succinyl CoA ligase [ADP forming] subunit beta,MTDPS5,Renal carcinoma antigen NY-REN-39,Renal carcinoma antigen NYREN39,SCS betaA,SCS-betaA,SUCB1,Succinate CoA ligase （ADP forming）,Succinate CoA ligase [ADP forming] subunit beta, mitochondrial; succinyl CoA ligase [ADP forming] subunit beta, mitochondrial,Succinate CoA ligase ADP forming beta subunit,Succinate CoA ligase beta subunit,Succinyl CoA ligase [ADP-forming] subunit beta, mitochondrial,Succinyl CoA synthetase beta A chain,Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial,Succinyl-CoA synthetase beta-A chain,SUCLA2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SUCLA2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：1000
Gene_ID（human）：8803
Swissprot：Q9P2R7
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction
