Background:The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
仕様
Synonyms:Cytoplasmic protein NCK1,Melanoma Nck protein,MGC12668,NCK 1,NCK adaptor protein 1,NCK alpha,NCK,NCK tyrosine kinase,Nck-1,NCK1,NCK1,NCKalpha,Non catalytic region of tyrosine kinase,SH2/SH3 adaptor protein NCK alpha,SH2/SH3 adaptor protein NCK-alpha
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human NCK1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:200
Gene_ID(human):4690
Swissprot:P16333
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Signal transduction