Background：The protein encoded by this gene is a member of the Toll-like receptor （TLR） family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns （PAMPs） that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
仕様
Synonyms：PRO285,TLR 7,Tlr7,TLR7,Toll like receptor 7,Toll-like receptor 7,UNQ248
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human TLR7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200 IF1：50 - 1：200
Gene_ID（human）：51284
Swissprot：Q9NYK1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
