Background：Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：ALPHA SUBUNIT,C polypeptide,EC 2.3.2.13,epididymis secretory protein Li 45,G alpha h,G[a]h,Gh CLASS G ALPHA h,GNAH,GNAH G PROTEIN,H POLYPEPTIDE,HEL-S-45,Protein glutamine gamma glutamyltransferase 2,Protein-glutamine gamma-glutamyltransferase 2,TG 2,TG（C）,TG2,TGase C,TGase H,TGase-2,TgaseII,TGC,TGC GUANINE NUCLEOTIDE BINDING PROTEIN,TGM2,TGM2,Tissue transglutaminase,Transglutaminase 2,Transglutaminase 2 C polypeptide,Transglutaminase C,Transglutaminase H,Transglutaminase-2,tTG,tTGas
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TGM2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：100 - 1：200
Gene_ID（human）：7052
Swissprot：P21980
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Immunology, Signal transduction
