Background：The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
仕様
Synonyms：80 kDa protein,80K L,80K L protein,80K-L protein,80KL,81 kDa protein,light chain,light chain,MACS,MARCKS,MARCS,MARCS,MGC52672,myristoylated alanine rich C kinase substrate,Myristoylated alanine rich protein kinase C substrate （MARCKS,80K L）,Myristoylated alanine rich protein kinase C substrate,Myristoylated alanine-rich C-kinase substrate,Phosphomyristin,PKCSL,PRKCSL,protein kinase C substrate 80 kDa protein light chain,Protein kinase C substrate
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human MARCKS
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4082
Swissprot：P29966
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction
