Background:The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:DKFZp781C1895,DKFZp781O1323,Dwfc,hSmad5,JV5 1,JV5-1,MAD homolog 5,MAD,mothers against decapentaplegic homolog 5,MADH 5,MADH5,Mothers against decapentaplegic homolog 5,mothers against decapentaplegic,drosophila,homolog of,5,Mothers against DPP homolog 5,MusMLP,SMA and MAD related protein 5,SMAD 5,SMAD family member 5,SMAD,mothers against DPP homolog 5,Smad5,SMAD5
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC
Concentration:1mg/ml
Immunogen:A synthetic peptide of human SMAD5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:IHC1:50 - 1:100
Gene_ID(human):4090
Swissprot:Q99717
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Signal transduction, Stem cells