Background：The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly（U） termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
仕様
Synonyms：Autoantigen La,La ,La autoantigen,La autoantigen homolog,La protein,La ribonucleoprotein,La ribonucleoprotein domain family member 3,LA,LARP3,Lupus La antigen,Lupus La protein,Lupus La protein homolog,MGC118101,MGC93380,mRNA for autoantigen,OTTMUSP00000014043,RP23 273G23.1,Sjoegren syndrome type B antigen,Sjogren syndrome antigen B （autoantigen La）,Sjogren syndrome antigen B,SS B,SS-B,SS-B/La protein,SSB
Host：Rabbit
Reactivity：Human
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human SSB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：1000 IHC1：100 - 1：200
Gene_ID（human）：6741
Swissprot：P05455
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology
