Background:This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仕様
Synonyms:Beta glycan,Betaglycan,Betaglycan proteoglycan,BGCAN,TGBR3,TGF beta receptor type 3,TGF beta receptor type III,TGF-beta receptor type 3,TGF-beta receptor type III,TGFB R3,TGFBR 3,TGFBR3,TGFR 3,TGFR-3,TGFR3,Transforming growth factor beta receptor III,Transforming growth factor beta receptor III betaglycan 300kDa,Transforming growth factor beta receptor type 3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human TGFBR3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.