Background:The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signaling. Multiple transcript variants have been found for this gene.
仕様
Synonyms:hSMAD6,MAD homolog 6,MADH6,MADH7,Mothers against decapentaplegic homolog 6,Mothers against DPP homolog 6,SMAD 6,SMAD family member 6,SMAD mothers against DPP homolog 6,Smad6,SMAD6
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human SMAD6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:1000
Gene_ID(human):4091
Swissprot:O43541
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells