Background:This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
仕様
Synonyms:ANOP3,cb236,Delta EF2a,lcc,MCOPS3,MGC148683,MGC2413,RGD1565646,Sex determining region Y box 2,SOX 2,Sox2,SOX2,SRY (sex determining region Y) box 2,SRY box containing gene 2,SRY related HMG box 2,SRY related HMG box gene 2,SRY-box 2,Transcription factor SOX 2,Transcription factor SOX-2,ysb
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human SOX2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.