Background：This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix （bHLH） domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：bHLHe37,Class E basic helix-loop-helix protein 37,MODED,mycn,MYCN,N myc,N myc proto oncogene protein,N-myc proto-oncogene protein,Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene,Neuroblastoma MYC oncogene,NMYC,NMYC proto oncogene protein,ODED,Oncogene NMYC,pp65/67,V myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog,v myc avian myelocytomatosis viral related oncogene neuroblastoma derived,v myc myelocytomatosis viral related oncogene neuroblastoma derived
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human MYCN
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：4613
Swissprot：P04198
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
