Background：The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly （ADP-ribose） polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
仕様
Synonyms：DNA repair protein XRCC1,RCC,X ray repair complementing defective repair in chinese hamster,X ray Repair Complementing Defective Repair in Chinese Hamster Cells,X ray repair complementing defective repair in chinese hamster cells 1,X ray repair cross complementing 1,X ray repair cross complementing protein 1,X ray repair,complementing defective,repair in Chinese hamster,X-ray repair cross-complementing protein 1,XRCC 1,Xrcc1,XRCC1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human XRCC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：1000 - 1：2000
Gene_ID（human）：7515
Swissprot：P18887
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism
