Background：This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
仕様
Synonyms：NR1B1,Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein,Nuclear receptor subfamily 1 group B member 1,Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form,RAR alpha,RAR,RAR-alpha,rara,RARA,RARalpha,RARalpha1,Retinoic acid nuclear receptor alpha variant 1,Retinoic acid nuclear receptor alpha variant 2,Retinoic acid receptor alpha,Retinoic acid receptor alpha polypeptide
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human RARA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：50 - 1：100
Gene_ID（human）：5914
Swissprot：P10276
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
