Background:This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
仕様
Synonyms:NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PRA,PRB,PRGR,Progesterone receptor,Progestin receptor form A,Progestin receptor form B
Host:Rabbit
Reactivity:Human,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PGR
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:200 - 1:500
Gene_ID(human):5241
Swissprot:P06401
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction