Background：This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal （NES）-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
仕様
Synonyms：Chromosome region maintenance 1 protein homolog,CRM 1,CRM1 homolog,DKFZp686B1823,emb,Exp 1,Exp1,Exportin 1,Exportin-1,Exportin1,XPO 1,xpo1,XPO1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human XPO1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：7514
Swissprot：O14980
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
