Background：The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
仕様
Synonyms：ALS,ALS1,Amyotrophic lateral sclerosis 1 adult,Cu/Zn SOD,Cu/Zn superoxide dismutase,Epididymis secretory protein Li 44,HEL S 44,Homodimer,hSod1,Indophenoloxidase A,IPOA,Mn superoxide dismutase,SOD,SOD soluble,SOD1,SOD2,SODC,SODC,Superoxide dismutase [Cu-Zn],Superoxide dismutase 1,Superoxide dismutase 1 soluble,Superoxide dismutase Cu Zn,Superoxide dismutase cystolic
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SOD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6647
Swissprot：P00441
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Signal transduction
