Background：The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases （ERKs）, act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
仕様
Synonyms：ERK 1,ERK,ERK-1,ERK1,ERT 2,ERT2,Extracellular Signal Regulated Kinase 1,Extracellular signal related kinase 1,Extracellular signal-regulated kinase 1,HGNC6877,HS44KDAP,HUMKER1A,Insulin Stimulated MAP2 Kinase,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP Kinase,MAP kinase isoform p44,MAPK 1,MAPK 3,MAPK,MAPK1,Mapk3,MGC20180,Microtubule Associated Protein 2 Kinase,Microtubule-associated protein 2 kinase,Mitogen Activated Protein Kinase 3,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 3,MK03,OTTHUMP00000174538,OTTHUMP00000174541,p44 ERK1,p44 MAPK,p44-ERK1,p44-MAPK,P44ERK1,P44MAPK,PRKM 3,PRKM3,Protein Kinase Mitogen Activated 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：A synthetic peptide of human MAPK3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：5595
Swissprot：P27361
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction, Stem cells
