Background：The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
仕様
Synonyms：APG 5,APG 5L,APG5,APG5 autophagy 5 like,APG5 like,APG5-like,APG5L,Apoptosis specific protein,Apoptosis-specific protein,ASP,ATG 5,Atg5,ATG5 autophagy related 5 homolog,ATG5,Autophagy protein 5,Autophagy related 5,hAPG5,Homolog of S Cerevisiae autophagy 5,OTTHUMP00000040507
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ATG5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：100
Gene_ID（human）：9474
Swissprot：Q9H1Y0
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
