Background:The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
仕様
Synonyms:MGC126760,MGC126762,PSCTK4 ,Tec,Tec protein tyrosine kinase,TEC,Tyrosine protein kinase,Tyrosine-protein kinase Tec
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human TEC
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.