Background：Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：（ALPHA）II-SPECTRIN,Alpha II Spectrin,Alpha-II spectrin,brain,EIEE5,FLJ17738,FLJ44613,Fodrin alpha chain,Fodrin,alpha,NEAS,Non erythrocytic spectrin alpha,non-erythroid alpha chain,SPECA,Spectrin alpha chain,Spectrin alpha chain brain,Spectrin alpha non erythrocytic 1,Spectrin,Spectrin non erythroid alpha chain,Spectrin,alpha,non-erythrocytic 1 （alpha-fodrin）,Spectrin,nonerythroid,alpha subunit,Spna2,SPTA 2,SPTA2,SPTA2,SPTAN 1,SPTAN1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human SPTAN1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6709
Swissprot：Q13813
Isotype：IgG
Research Areas：Cancer, Signal transduction, Tags ＆ Cell Markers
