Background:This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
仕様
Synonyms:AF6q21,AF6q21 protein,DKFZp781A0677,FKHR2,FKHRL 1,FKHRL1,FKHRL1P2,Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1,Forkhead box O3,Forkhead box O3A,Forkhead box protein O3,Forkhead box protein O3A,Forkhead Drosophila homolog of in rhabdomyosarcoma like 1,Forkhead homolog (rhabdomyosarcoma) like 1,Forkhead in rhabdomyosarcoma like 1,Forkhead in rhabdomyosarcoma-like 1,FOX O3A,FOXO2,foxo3,FOXO3,FOXO3A,MGC12739,MGC31925
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of mouse FOXO3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):56484
Swissprot:Q9WVH4
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling