Background:This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Epididymis luminal protein 215,Epididymis secretory sperm binding protein Li 54e,HEL 215,HEL S 54e,PHB,PHB,PHB1,Prohibitin
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PHB
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):5245
Swissprot:P35232
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Tags & Cell Markers