Background：This gene encodes a member of the epidermal growth factor （EGF）- Cripto, Frl-1, and Cryptic （CFC） family, which are involved in signaling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：CFC 1,CFC1,CFC1,CFC1B,CR 1,Cripto 1,Cripto FRL 1 cryptic family 1,CRYPTIC,Cryptic family 1,Cryptic family protein 1,Cryptic gene,Cryptic protein,DTGA2,FLJ77897,FRL 1,Heterotaxy 2 （autosomal dominant）,HTX2,MGC133213
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human CFC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
