Background：E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.
仕様
Synonyms：CBX 4,CBX4,Cbx4 chromobox homolog 4 （Drosophila Pc class）,CBX4,Chromobox homolog 4 （Pc class homolog,Drosophila）,Chromobox homolog 4,Chromobox protein homolog 4,E3 SUMO protein ligase CBX 4,E3 SUMO protein ligase CBX4,E3 SUMO-protein ligase CBX4,hPc 2,hPc2,NBP 16,NBP16,NS5ATP1 binding protein 16,Pc 2,Pc class 2 homolog,Pc class homolog,Pc class homolog Drosophila,PC2,Polycomb 2 homolog
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.7mg/mL
Immunogen：Synthetic peptide of human CBX4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-2000, ELISA 1：2000-5000
Swissprot：O00257
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
