Background：This gene encodes a member of the ADAMTS （a disintegrin and metalloproteinase with thrombospondin motif） protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 （TS） motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
仕様
Synonyms：C3-C5,METH1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human ADAMTS1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：Q9UHI8
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Signal transduction, Tags ＆ Cell Markers
