Background：ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 （zinc finger DNA-binding protein 99）, is a zinc finger protein that belongs to the Kruppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC （ornithine decarboxylase）. In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.
仕様
Synonyms：GC box binding zinc finger protein 1,GC-box-binding zinc finger protein 1,GZP1,Transcription factor ZBP-99,ZBP 99,ZBP99,zfp281,Zinc finger DNA binding protein 99,Zinc finger DNA-binding protein 99,Zinc finger protein 281,ZN281,ZNF281,ZNP 99,ZNP 99 transcription factor,ZNP99
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human ZNF281
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：Q9Y2X9
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
