Background:Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).
仕様
Synonyms:VAM1,p55T,PALS2,VAM-1
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human MPP6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:30-150, ELISA 1:2000-10000
Swissprot:Q9NZW5
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling