Background:Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
仕様
Synonyms:Liver specific uridine phosphorylase,UDRPASE2,UP2,UPase 2,UPASE2,UPP 2,UPP2,UPP2,UrdPase 2,Uridine phosphorylase 2
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.9mg/mL
Immunogen:Synthetic peptide of human UPP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:30-150, ELISA 1:1000-2000
Swissprot:O95045
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Metabolism, Signal transduction