Background:This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients witHuman, Mouseultiple myeloma.
仕様
Synonyms:SK,DKK-1
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Synthetic peptide of human DDK1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-100, ELISA 1:2000-5000
Swissprot:O94907
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Developmental biology, Immunology, Stem cells