Background:The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker.
仕様
Synonyms:B19,Bstk1,Hormonally up-regulated neu tumor-associated kinase,Hormonally upregulated neu associated kinase,Hormonally upregulated neu tumor associated kinase,HUNK,HUNK,MAKV,Serine/threonine-protein kinase MAK-V
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human HUNK
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-100, ELISA 1:2000-5000
Swissprot:P57058
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction