Background：This gene encodes a member of the tripartite motif （TRIM） family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.
仕様
Synonyms：AW538890,DAAP-182E11.3,MGC189472,OTTHUMP00000029314,Ret finger protein,RFP,RFP transforming protein,Rfp1,RING finger protein 76,RNF76,TRI27,TRIM 27,Trim27,Tripartite motif containing 27,Tripartite motif containing protein 27,Tripartite motif protein TRIM27,Tripartite motif-containing protein 27,Zinc finger protein RFP
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human TRIM27
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：P14373
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
