Background：Ubiquitin-like molecules （UBLs）, such as SUMO1 （UBL1; MIM 601912）, are structurally related to ubiquitin （MIM 191339） and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 （MIM 602362） to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha （NFKBIA; MIM 164008） from degradation by the 26S proteasome.
仕様
Synonyms：2810017C20Rik,FLJ11355,FLJ11887,KIAA0389,KIAA0797,SENP 6,Senp6,SENP6,Sentrin specific protease 6,Sentrin-specific protease 6,Sentrin/SUMO specific protease SENP6,Sentrin/SUMO-specific protease SENP6,SSP 1,SSP1,SUMO 1 specific protease 1,SUMO 1 specific protease,SUMO-1-specific protease 1,SUMO1 specific protease 1,SUMO1 specific protease,SUMO1/sentrin specific peptidase 6,SUSP 1,SUSP1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human SENP6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1000, ELISA 1：1000-2000
Swissprot：Q9GZR1
Isotype：IgG
Research Areas：Cell Biology, Epigenetics and Nuclear Signaling
