Background:RCC1 (regulator of chromosome condensation 1), increases the rate at which Ran exchanges GDP for GTP. Ran GAP1 opposes the effects of RCC1 by increasing the rate at which Ran hydrolyzes GTP to GDP. A protein designated Ran BP1 has no intrinsic GAP activity and functions as a GEF inhibitor, deactivating RCC1 and thereby indirectly increasing the ratio of Ran GDP to Ran GTP. Ran BP2 has been proposed as the Ran GTP docking site at the periphery of the nuclear pore complex.
仕様
Synonyms:Cell cycle regulatory protein,CHC 1,CHC1,Chromosome condensation 1,Chromosome condensation protein 1,Guanine nucleotide releasing protein,HERC2,Ran GEF,RanGEF,RCC 1,RCC1,RCC1 I,RCC1,Regulator of chromosome condensation 1,Regulator of chromosome condensation,SHEP1,SNHG3 RCC1,SNHG3 RCC1 readthrough transcript
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human RCC1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3