Background：This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure （CRF）, and this may be one of the factors underlying the degenerative processes （e.g., arteriosclerosis, osteoporosis, and skin atrophy） seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
仕様
Synonyms：Kl,KLOT,Klotho peptide
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human KL
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1000, ELISA 1：1000-2000
Swissprot：Q9UEF7
Isotype：IgG
Research Areas：Cancer, Metabolism, Developmental biology, Signal transduction
