Background:SHANK1 seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
仕様
Synonyms:GKAP/SAPAP interacting protein,OTTHUMP00000174437,SH3 and multiple ankyrin repeat domains 1,SH3 and multiple ankyrin repeat domains protein 1,SH3/ankyrin domain gene 1,SHAN1,SHANK 1,Shank1,Shank1a,Somatostatin receptor interacting protein,Somatostatin receptor-interacting protein,SPANK 1,SPANK1,SSTR interacting protein,SSTR-interacting protein,SSTRIP,Synamon
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human SHANK1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3