Background：KDM6B （Lysine demethylase 6B） is a 1,679 amino acid nuclear protein that contains one JmjC domain and belongs to the highly conserved JmjC domain-containing protein family. Functioning as a histone demethylase, JMJD3 uses iron and ascorbate as cofactors to demethylate dimethylated and trimethylated Lys-27 residues of Histone H3, thereby playing an important role in the modification of the histone code.
仕様
Synonyms：Histone demethylase JMJD3,JmjC domain containing protein 3,JmjC domain-containing protein 3,Jumonji D3,Jumonji domain containing 3,Jumonji domain containing 3 histone lysine demethylase,Jumonji domain containing protein 3,Jumonji domain-containing protein 3,Kdm6b,KDM6B,KIAA0346,Lysine demethylase 6B,Lysine K specific demethylase 6B,Lysine specific demethylase 6B,Lysine-specific demethylase 6B
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human KDM6B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1000, ELISA 1：1000-2000
Swissprot：O15054
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
