Background：This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate （NMDA） receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：EPND,FESD,GluN2A,Glutamate [NMDA] receptor subunit epsilon-1,Glutamate receptor,Glutamate receptor ionotropic N methyl D aspartate 2A,GRIN 2A,GRIN2A,hNR2A,LKS,N methyl D aspartate receptor channel,subunit epsilon 1,N Methyl D Aspartate Receptor Subtype 2A,N methyl D aspartate receptor subunit 2A,N-methyl D-aspartate receptor subtype 2A,NMDA receptor subtype 2A,NMDAR 2A,NMDAR2A,NMDE1,NR2A,OTTHUMP00000160135,OTTHUMP00000174531
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human GRIN2A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
