Background：This gene is a member of the insulin-like growth factor binding protein （IGFBP） family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit （IGFALS） and either insulin-like growth factor （IGF） I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：Acid stable subunit of the 140 K IGF complex,Binding protein 29,Binding protein 53,BP 53,BP53,Growth hormone dependent binding protein,IBP 3,IBP-3,IBP3,IBP3,IGF binding protein 3,IGF-binding protein 3,IGFBP 3,IGFBP-3,IGFBP3,Insulin Like Growth Factor Binding Protein 3,Insulin-like growth factor binding protein 3 precursor,Insulin-like growth factor-binding protein 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：1.6mg/mL
Immunogen：Synthetic peptide of human IGFBP3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：P17936
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Metabolism, Signal transduction
