Background：This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins.
仕様
Synonyms：High mobility group （nonhistone chromosomal） protein isoforms I and Y,High mobility group AT hook 1,High mobility group AT-hook protein 1,High mobility group protein 1,High mobility group protein A1,High mobility group protein HMG-I/HMG-Y,High mobility group protein Ia,High mobility group protein R,HMG R,HMG-I（Y）,HMGA1,HMGA1,HMGA1A,HMGIY,MGC12816,MGC4242,MGC4854,Nonhistone chromosomal high mobility group protein HMG I/HMG Y
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human HMGA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-2000, ELISA 1：2000-5000
Swissprot：P17096
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Microbiology
