Background：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
仕様
Synonyms：ARO,ARO1,Aromatase,CP19A,CPV1,CYAR,CYP19,Cyp19a1,CYPXIX,Cytochrome P-450AROM,Cytochrome P450 19A1,Cytochrome P450,family 19,subfamily A,polypeptide 1,Cytochrome P450,subfamily XIX （aromatization of androgens）,Estrogen synthase,Estrogen synthetase,Flavoprotein linked monooxygenase,MGC104309,Microsomal monooxygenase,OTTHUMP00000162543,OTTHUMP00000198350,P 450AROM
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human CYP19A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：P11511
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience
