Background:UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
仕様
Synonyms:EC 2.4.1.17,HLUG25,Hyodeoxycholic acid,Hyodeoxycholic acid specific UDPGT,UDP glucuronosyltransferase 2 family polypeptide B4,UDP glucuronosyltransferase 2B4,UDP glucuronosyltransferase 2B4 precursor,UDP glucuronyltransferase family 2 beta 4,UDP glycosyltransferase 2 family polypeptide B4,UDP glycosyltransferase,UDPGT,UDPGT 2B4,UDPGT2B4,UDPGTh 1,UDPGTh1,UGT2B11,UGT2B4
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Fusion protein of human UGT2B4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:30-150, ELISA 1:2000-10000
Swissprot:P06133
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction