Background：Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 （By similarity）.
仕様
Synonyms：FLJ10128,KIAA1561,MGC141967,MGC141969,Nuclear membrane binding protein,NUCLING,UACA,UACA,Uveal autoantigen with coiled coil domains and ankyrin repeats,Uveal autoantigen with coiled-coil domains and ankyrin repeats
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Fusion protein of human UACA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
