Background:Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
仕様
Synonyms:Endoplasmic reticulum resident protein 44,Endoplasmic reticulum resident protein 44 kDa,Endoplasmic reticulum resident protein ERp44,ER protein 44,ERp44,ERP44,KIAA0573,PDIA10,Protein disulfide isomerase family A,member 10,Thioredoxin domain containing 4 (endoplasmic reticulum),Thioredoxin domain containing protein 4,Thioredoxin domain-containing protein 4,UNQ532/PRO1075
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Fusion protein of human ERP44
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-100, ELISA 1:2000-5000
Swissprot:Q9BS26
Isotype:IgG
Research Areas:Cell Biology, Metabolism, Signal transduction