Background:The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.
仕様
Synonyms:bHLHa39,Class A basic helix-loop-helix protein 39,Dermis expressed protein 1,Dermis-expressed protein 1,DERMO 1,Dermo-1,DERMO1,MGC117334,Twist 2,Twist homolog 2 (Drosophila),Twist homolog 2,Twist related bHLH protein Dermo1,Twist related protein 2,Twist-related protein 2,Twist2,TWST2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Full length of human TWIST2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-100, ELISA 1:2000-5000
Swissprot:Q8WVJ9
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Stem cells