Background:This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
仕様
Synonyms:MGC10556,MGC10558,MGC29959,MGC3837,MGC4423,OIP-1,OIP1,OPA interacting protein 1,OPA-interacting protein 1,Thyroid hormone receptor interactor 6,Thyroid receptor interacting protein 6,Thyroid receptor-interacting protein 6,TR-interacting protein 6,TRIP-6,Trip6,TRIP6,TRIP6i2,ZRP 1,ZRP-1,Zyxin-related protein 1
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.8mg/mL
Immunogen:Fusion protein of human TRIP6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:30-150, ELISA 1:2000-10000
Swissprot:Q15654
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Signal transduction