Background:This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
仕様
Synonyms:RING finger protein 206,RNF206,TRAF Interacting Protein,TRAF-interacting protein,Traip,TRAIP,TRIP
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Fusion protein of human TRAIP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:30-150, ELISA 1:2000-10000
Swissprot:Q9BWF2
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling