Background：The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
仕様
Synonyms：C20orf97,Neuronal cell death inducible putative kinase,Neuronal cell death-inducible putative kinase,NIPK,p65 interacting inhibitor of NF-kappaB,p65-interacting inhibitor of NF-kappa-B,SINK,SKIP 3,SKIP3,TRB 3,TRB-3,TRB3,TRIB 3,Trib3,TRIB3,Tribbles homolog 3,Tribbles pseudokinase 3,Tribbles3
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Full length fusion protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：Q96RU7
Isotype：IgG
Research Areas：Cell Biology, Cardiovascular, Signal transduction
